Context: India first dengue vaccine UPSC
The Drug Controller General of India has granted market authorisation to QDENGA (TAK-003), making it India’s first approved dengue vaccine for individuals aged 4–60 years.
The vaccine can be administered irrespective of prior dengue infection and does not require pre-vaccination screening.
QDENGA Vaccine
Developed By
Takeda Biopharmaceuticals.
Type
QDENGA is a live-attenuated tetravalent vaccine.
Protection
It provides protection against all four dengue virus serotypes:
- DENV-1
- DENV-2
- DENV-3
- DENV-4
Dose Schedule
It is administered as a two-dose regimen.
The two doses are given three months apart.
Approval Status
The vaccine has been approved for use in 43 countries and is supported by Phase III clinical trial data.
Dengue
Dengue is a viral disease caused by the dengue virus.
It is mainly transmitted by the female Aedes aegypti mosquito.
It can also be transmitted by Aedes albopictus.
Symptoms
Common symptoms include:
- High fever
- Severe headache
- Muscle pain
- Joint pain
- Skin rash
Severe dengue may cause:
Treatment and Prevention
There is no specific antiviral treatment for dengue.
Management is mainly supportive and includes:
- Early diagnosis
- Adequate fluid therapy
- Monitoring of warning signs
Prevention focuses on:
- Vector control
- Elimination of mosquito breeding sites
- Protection against mosquito bites
Significance
1. Public Health Milestone
India now has its first approved dengue vaccine for a wide age group.
2. Supports Disease Prevention
Vaccination can reduce severe disease burden if implemented effectively.
3. Important for Dengue-Endemic Areas
Dengue remains a major public health issue in India, especially during and after the monsoon season.
4. Reduces Pressure on Health Systems
Preventing dengue infections and severe cases can reduce hospitalisation burden.
Key Takeaway
QDENGA’s approval is a major step in dengue prevention, but vector control, surveillance and public awareness will remain essential.
Millions of people die every year due to mosquitoes. It is best to prevent then to cure. Vaccines are upgraded and so does the diseases. It is better to prevent mosquitoes using mosquito net, keeping our house and surroundings clean. Stagnant water is the main cause.